Respiration
By Naomi Keddy
Respiration is the enzyme controlled release of energy
from food within all living cells. 
There are two Types of
respiration: 
1.      
Aerobic
Respiration – Which is the controlled
release of energy from cells that requires the presence of oxygen. 
Balanced equation:
C6H12O6+6O2→6CO2+6H2O+2820kJ 
Glucose + Oxygen → Carbon Dioxide + Water
+ Energy 
Aerobic
respiration:
 -It uses oxygen. 
-It
releases carbon dioxide and water. 
-It releases a large amount of
energy. 
2. Anaerobic Respiration – Which is the controlled release of energy from cells
that thrive in the absence of oxygen. 
Anaerobic Respiration:
-It doesn’t require oxygen
-It releases a small amount of energy
There are two types of
Anaerobic Respiration: 
1. Alcohol fermentation in
yeast 
Equation:
Glucose → Alcohol + Carbon
Dioxide + Small amount of energy 
2. Lactic acid fermentation 
Equation:
Glucose → Lactic acid + small
amount of energy 
The Use of
Micro-Organisms in Industrial Fermentation:
Biotechnology
is the use of living
things or their components (cells and enzymes) to make useful products. 
Bioreactors: This is the
vessel in which the biological reactions take place.
Examples of
Bioprocessing
Micro-organism
Product Use 
Bacteria
Yoghurt Food 
Antibiotics
Kills Bacteria 
Hormones
Maintains health (e.g. insulin) 
Yeast Ethanol
Beer and Wine 
Carbon Dioxide
Rises Dough 
.
 Stages of Aerobic Respiration:
There are
three stages to be considered. 
1. Glycolysis 
2. Krebs Cycle 
3. Electron Transport System
Stage 1:
Glycolysis 
- Glycolysis occurs in the absence of
oxygen. 
-During glycolysis, glucose is broken down into two molecules of a 3-Carbon compound called pyruvic
acid 
Stage 2: Kreb’s Cycle 
- Pyruvic
acid from
glycolysis enters the lumen of the mitochondrion where it loses carbon dioxide to
become acetyl co-enzyme A (C2)
- Acetyl Co-Enzyme A enters the Kreb’s
cycle. 
- The Kreb’s cycle is a series of
chemical reactions which result in the loss of carbon dioxide and pairs of
hydrogen atoms (electrons and protons). 
- The carbon dioxide is excreted. 
- The pairs of hydrogen atoms Two high
energy electrons and H+ are picked up by NAD+ to form NADH which enters the
membranes of the cristae of the mitochondrion where oxidative phosphorylation
takes place.
Stage 3:
Electron transport system:
- The pairs if hydrogen atoms picked up
by the NAD+ from glycolysis and the Kreb’s cycle are carried into the membranes
of the cristae of the mitochondrion. 
- Pairs of electrons are passed down
the carrier system (electron transport system) releasing energy used in
phosphorylation. 
- Here they are passed along a system
of electron carriers.
- As electrons are transferred from one
carrier to another enough energy is released to phosphorylate ADP to ATP three
times. 
- At the end of the chain, the
electrons and H+ are combined with oxygen to form water. 
 Glycolysis
- It takes place in the cytoplasm.
-Oxygen is not used.
- It takes place in aerobic and anaerobic respiration.
 Kreb’s Cycle
- It takes place in the lumen of the mitochondrion.
- It only occurs in aerobic respiration.
Electron transport system:
- It takes place on the cristae of the
mitochondrion. 
- It only occurs in the presence of
oxygen. 
- Vitamins of the B group are required
to make carriers 1 and 2
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